Combinatorial biosynthesis is a research area that involves the manipulation and engineering of biological systems, such as microorganisms or plants, to create novel chemical compounds or drugs. By combining different genetic elements or pathways, researchers can generate a wide range of unique molecules with diverse biological activities. This approach allows for the rapid exploration of chemical space and the discovery of potentially valuable compounds for various applications, including drug development, agriculture, and industrial processes. Combinatorial biosynthesis is often used in combination with high-throughput screening methods to identify promising candidates for further study and optimization.